Endocrine Abstracts

Introduction: Nodular thyroid disease is common in the general population, but only 5% of thyroid nodules are carcinomas. The diagnostic challenge is to identify those nodules that are malignant neoplasias. Some sonographic features of nodules have been correlated with the risk of malignancy, but at present, thyroid cytology obtained by ultrasound-guided FNA is probably the best tool in the preoperative management of nodular disease.Design: We designed a...

Papillary thyroid cancer (PTC) is the most common endocrine malignancy. Its management has not changed significantly in recent decades, and most patients receive the same treatment. Moreover, there are not alternative treatments for low response or aggressive neoplasias. The availability of reliable prognostic markers that would allow the PTC to be identified based on their aggressiveness at the time of diagnosis would derive in an individualized treatment. In a previous study...

Retinoic acid (RA) treatment has been used in the last decade for redifferentiation of metastatic thyroid cancer that have lost radioiodine uptake (RIup) with heterogeneous results.Aim: To evaluate the improvement of RIup after a course of RA treatment.Method: Retrospective analysis of 29 patients with radioiodine negative metastatic disease (17 men /12 women; 22 papillary, 4 follicular and 3 oncocytic tumours). RA was given at a d...